Tools to precisely determine T cell differentiation states are of clinical relevance when T cells contribute to immune control and/or disease. Researchers from CMM have performed a meticulous study of the transitions between CD8+ T cell differentiation states. They found that the expression level of the chemokine receptor CX3CR1 predicts the skills of the individual T cells. Importantly, CX3CR1 expression levels identify functionally comparable T cell states in mice and humans. The resulting article was recently published in the journal Immunity.
Early treatment of the chronic inflammatory joint disease rheumatoid arthritis (RA) is as-sociated with improved outcome in recently diagnosed patients. In a study recently pub-lished in Annals of the Rheumatic Diseases CMMer Jon Lampa and colleagues compared the clinical outcomes of active conventional therapy with three different biological treat-ments. Two of the biological drugs showed better results in comparison to conventional therapy and could be considered in the future management of patients with newly diagnosed RA.
For CMM L8 building-related emergencies (eg. water leak, CO2) and low temperature freezer issues, please call the Caverion remote center:
010-480 88 08