CRISPR/Cas9 gene editing is a promising technique in the rapidly developing field of precision medicine. In a recent publication, the CMMers Long Jiang (PhD Student), Fredrik Wermeling (Team Leader), and co-authors show that the editing technique can lead to the enrichment of cells with mutations in a broad p53-linked network of cancer-related genes.
Åsa Wheelock, Team Leader at CMM, has received SEK 3 million from the Swedish Research Council within the category of postcovid research. The awarded project led by Åsa, aims at developing a home monitoring system to facilitate continuous follow-up of long-COVID patients. The system will also be used to evaluate the effectiveness of various forms of treatment.
Patients with type 2 diabetes develop damage to the blood vessels over time, which in turn increases the risk for blood cloths and complications such as heart attack and stroke. The mechanisms behind the vascular injury are however unknown. In a study published in Diabetes, CMM researchers Zhichao Zhou and John Pernow show that the effect is caused by low levels of the molecule microRNA-210 in red blood cells of type 2 diabetes patients and mice.
Friday 26 November
Title: The red blood cell as a mediator of vascular injury in Type 2 Diabetes and COVID-19
Speaker: Ali Mahdi
The CVP/CVR and Heart and Vascular Theme Joint Meeting 2021
The CMMers Anton Gisterå and Carolina Hagberg, are part of the organizing committee, and invite you to participate in this external event.
Thursday 2 December
Title: Immune Responses Targeting Therapeutic and Endogenous Antibodies: Characteristics and Clinical Implications
Speaker: Theo Rispens, Sanquin Research, Department of Immunopathology, Amsterdam
Friday 3 December
Title: Immunogenicity of Biological Therapies; Frequency, Predictability and Clinical Relevance in Chronic Inflammatory Diseases
Speaker: Nicky Dunn
Monday 6 December
Title: Inspiration and Inflammation in the Breathing Brainstem
Speaker: Jan Philipp Reising
Monday 6 December
Seminars on Translational Neuroimaging
(StratNeuro Lunch Seminar Series)
Speakers: Johan Lundström, CNS, Karolinska Institutet and Daniel Ferreira Padilla, NVS, Karolinska Institutet
The CMMer Vasco Souza invites you to participate in this external event.
Friday 9 December
Title: The role of smooth muscle cells in calcification of atherosclerotic plaques
Speaker: Till Seime