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The Eidsmo laboratory explores mechanisms that dictate the fine-tuned balance between health and focal immunopathology in human skin. The skin barrier is constantly exposed to colonizing microbiota, invasive pathogens, and allergens and immune cells interacts with stroma to protect against microbial invasion. Additionally, the immune system is heavily implicated in common patchy inflammatory diseases such as vitiligo and psoriasis. In healthy skin, the Eidsmo laboratory defined functionally distinct subsets of tissue resident memory T (Trm) cells based on their expression of the integrin CD49a. In diseases such as vitiligo and psoriasis, different subsets of pathogenic Trm cells form localized disease memories in resolved skin.

Right now we focus on how human Trm cells are formed and how these cells impact on their immediate environment. Ultimately, we want to normalise the Trm cell compartment in diseased skin to reach robust and long-term homeostasis. 



To be updated


Liv Eidsmo

Graduated from medical school 1999 and defended my PhD in Immunobiology at Karolinska Instituet 2006.

Postdoc in Frank Carbone's laboratory at Melbourne University in Australia 2007-09.

Returned to Sweden to build the Eidsmo laboratory at CMM in parallel to clinical training in Dermatology and Venerology at Karolinska University Hospital in 2010. 

Board certified Dermatologist in 2017 and since 2019 a Dermatologist at Diagnostiskt Centrum Hud, Stockholm.

Associate Professor in Dermatology and Venereology at Karolinska Institutet 2014.

Professor in Translational Skin Immunology at Copenhagen University from 2021.

The Eidsmo laboratory will be placed at CMM Karolinska Institutet and at the Leo Foundation Skin Immunology Center at Copenhagen University from 2021.  


Liv Eidsmo Lab at Copenhagen Uni

To be updated


Academic Honors, Awards and Prizes

2017    Ellis and Ivar Janzons prize, The Swedish Society of Medicine

2016    Marcus and Marianne Wallenberg Clinical Research Fellow

2014    Ragnar Söderberg Research Fellow

2013    The Dermatology Prize, awarded by the Swedish Society of Dermato-Venerology  (SSDV) and Novartis

2010    The Psoriasis Prize, awarded by SSDV and MSD2009      Young Investigator Award, The Karolinska Institutet’s Foundation.

2006    Elected as Honorary Speaker during the Karolinska Institutet's Official PhD Ceremonies.

Selected Publications

Koguchi-Yoshioka H, Hoffer E, Cheuk S, Matsumura, Vo S, Kjellman P, Grema L, Ishitsuka Y, Nakamura Y, Okiyama N, Fujisawa Y, Fujimoto F, Eidsmo L†, Clark RA†, Watanabe R†. Human T cells remain diverse and highly functional in the aged skin. Communications Biology, In Press †Shared senior authors.

Gallais Sérézal I,  Hoffer E,  Ignatov B,  Martini E,  Zitti B,  Ehrström M,  Eidsmo L. A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional skin from patients with psoriasis. The Journal of allergy and clinical immunology 2019 143;4 1444-1454

Schulz A,  Jiang L,  de Vor L,  Ehrström M,  Wermeling F,  Eidsmo L,  Melican K. Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization. Cell reports 2019 29;5 1074-1081.e5

Gallais Sérézal I,  Classon C,  Cheuk S,  Barrientos-Somarribas M,  Wadman E,  Martini E,  Chang D,  Xu Landén N,  Ehrström M,  Nylén S,  Eidsmo L. Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome. The Journal of investigative dermatology 2018 138;8 1754-1763

Cheuk S,  Schlums H,  Gallais Sérézal I,  Martini E,  Chiang SC,  Marquardt N,  Gibbs A,  Detlofsson E,  Introini A,  Forkel M,  Höög C,  Tjernlund A,  Michaëlsson J,  Folkersen L,  Mjösberg J,  Blomqvist L,  Ehrström M,  Ståhle M,  Bryceson YT,  Eidsmo L. CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin. Immunity 2017 46;2 287-300

Martini E,  Wikén M,  Cheuk S,  Gallais Sérézal I,  Baharom F,  Ståhle M,  Smed-Sörensen A,  Eidsmo L. Dynamic Changes in Resident and Infiltrating Epidermal Dendritic Cells in Active and Resolved Psoriasis. The Journal of investigative dermatology 2017 137;4 865-873

Cheuk S,  Wikén M,  Blomqvist L,  Nylén S,  Talme T,  Ståhle M,  Eidsmo L. Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasis. Journal of immunology (Baltimore, Md. : 1950) 2014 192;7 3111-20

Eidsmo L,  Stock AT,  Heath WR,  Bedoui S,  Carbone FR. Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics. Journal of Pathology 2012 226;5 806-13

Eidsmo L,  Allan R,  Caminschi I,  van Rooijen N,  Heath WR,  Carbone FR. Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection. Journal of Immunology 2009 182;5 3165-72

Gebhardt T,  Wakim LM,  Eidsmo L,  Reading PC,  Heath WR,  Carbone FR. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nature Immunology 2009 10;5 524-30


Eidsmo L,  Martini E. Human Langerhans Cells with Pro-inflammatory Features Relocate within Psoriasis Lesions. Frontiers in immunology 2018 9; 300-

Nylen S,  Eidsmo L. Tissue damage and immunity in cutaneous leishmaniasis. Parasite Immunology 2012 34;12 551-61

Editorial Comments

Eidsmo L, Gerlach C. Heavy Water Shedding Light on Antigen-Specific T Cell Responses. Trends in Immunology 2018 39;3 170-172

Cheuk S,  Eidsmo L. The Skinny on Fat Trm Cells. Immunity 2017 47;6 1012-1014

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